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MRK 560 MeSH Supplementary Concept Data 2024


MeSH Supplementary
MRK 560
Unique ID
C510791
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/C510791
Entry Term(s)
MRK-560
MRK560
N-(4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)-1,1,1-trifluoromethanesulfonamide
Pharm Action
Gamma Secretase Inhibitors and Modulators
Registry Number
0
Previous Indexing
*SULFONES (2006-2008)
Heading Mapped to
*Sulfonamides
Frequency
13
Note
a gamma-secretase inhibitor; MRK-560 is the (cis)-isomer; structure in first source
Source
J Pharmacol Exp Ther 2006 May;317(2):786-90
Date of Entry
2006/06/07
Revision Date
2021/08/09
MRK 560 Preferred
N-(4-((4-chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)-1,1,1-trifluoromethanesulfonamide Broader
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