Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Alarmins MeSH Descriptor Data 2025


MeSH Heading
Alarmins
Tree Number(s)
D23.469.025
Unique ID
D000067531
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000067531
Scope Note
A structurally diverse group of endogenous molecules that are multifunctional, having physiological functions inside the cell, but when released from dying cells or from cells under stress or certain immune cells, they function to activate INNATE IMMUNITY. Uncontrolled and excessive release of alarmins may contribute to INFLAMMATION; CARCINOGENESIS, and NEOPLASM METASTASIS. Alarmins are also critical for heart and nerve tissue homeostasis.
Entry Term(s)
Alarmin
Alarmin Proteins
Damage-Associated Molecular Pattern Molecules
Danger-Associated Molecular Pattern Molecules
Registry Numbers
0
Previous Indexing
HMGB1 Protein (2004-2015)
Public MeSH Note
2016
History Note
2016
Date Established
2016/01/01
Date of Entry
2015/07/01
Revision Date
2021/07/07
Alarmins Preferred
page delivered in 0.162s