MeSH Browser

MeSH Heading: CELF1 Protein
Tree Number(s): D12.776.157.725.813.250.500; D12.776.664.962.813.250.500
Unique ID: D000067879
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000067879
Scope Note: A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1.
Entry Term(s): BRUNOL2 Protein; Bruno-Like 2 Protein; CUG Triplet Repeat, RNA-Binding Protein 1; CUGBP, Elav-Like Family Member 1 Protein; CUGBP1 Protein
Registry Numbers: 0
Previous Indexing: Ribonucleoproteins (1997-2004); RNA-Binding Proteins (2005-2015)
Public MeSH Note: 2016
History Note: 2016
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2015/02/26

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000601218
Registry Numbers: 0
Scope Note: A member of the CELF PROTEINS family which binds GU rich elements (GREs) and CUG-triplet repeats in the 3'UTR of mammalian mRNA transcripts that undergo rapid turnover. It also binds AU-rich elements (AREs or EDEN-like) in the 3'UTR of JUN and FOS mRNAs. Mutations in the human CELF1 gene are associated with MYOTONIC DYSTROPHY type 1.
Terms: CELF1 Protein Preferred Term
Term UI T000873177
Date01/05/2015
LexicalTag ABX
ThesaurusID NLM (2016); BRUNOL2 Protein
Term UI T000874574
Date02/02/2015
LexicalTag ABX
ThesaurusID NLM (2016); CUG Triplet Repeat, RNA-Binding Protein 1
Term UI T000874575
Date02/02/2015
LexicalTag NON
ThesaurusID NLM (2016); CUGBP, Elav-Like Family Member 1 Protein
Term UI T000874576
Date02/02/2015
LexicalTag ABX
ThesaurusID NLM (2016); CUGBP1 Protein
Term UI T000874577
Date02/02/2015
LexicalTag ABX
ThesaurusID NLM (2016); Bruno-Like 2 Protein
Term UI T000874578
Date02/02/2015
LexicalTag NON
ThesaurusID NLM (2016)

CELF1 Protein MeSH Descriptor Data 2025