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Fingolimod Hydrochloride
MeSH Descriptor Data 2024
Details
Qualifiers
MeSH Tree Structures
Concepts
MeSH Heading
Fingolimod Hydrochloride
Tree Number(s)
D02.033.100.700.350
D02.033.455.706.431
D02.092.063.700.350
Unique ID
D000068876
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000068876
Scope Note
A sphingosine-derivative and
IMMUNOSUPPRESSIVE AGENT
that blocks the migration and homing of
LYMPHOCYTES
to the
CENTRAL NERVOUS SYSTEM
through its action on
SPHINGOSINE 1-PHOSPHATE RECEPTORS
. It is used in the treatment of
MULTIPLE SCLEROSIS
.
Entry Term(s)
2-Amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride
FTY 720
FTY-720
FTY720
Fingolimod
Gilenia
Gilenya
Pharm Action
Sphingosine 1 Phosphate Receptor Modulators
Immunosuppressive Agents
Registry Number
G926EC510T
Related Numbers
162359-56-0
3QN8BYN5QF
Public MeSH Note
2016; FINGOLIMOD HYDROCHLORIDE was indexed under PROPYLENE GLYCOLS and SPHINGOSINE 1996-2015
History Note
2016 (1996)
Date Established
2016/01/01
Date of Entry
2015/07/06
Revision Date
2019/06/17
Allowable Qualifiers
administration & dosage (AD)
adverse effects (AE)
agonists (AG)
analogs & derivatives (AA)
analysis (AN)
antagonists & inhibitors (AI)
blood (BL)
cerebrospinal fluid (CF)
chemical synthesis (CS)
chemistry (CH)
classification (CL)
economics (EC)
history (HI)
immunology (IM)
isolation & purification (IP)
metabolism (ME)
pharmacokinetics (PK)
pharmacology (PD)
poisoning (PO)
radiation effects (RE)
standards (ST)
supply & distribution (SD)
therapeutic use (TU)
toxicity (TO)
urine (UR)
Organic Chemicals [D02]
Alcohols [D02.033]
Amino Alcohols [D02.033.100]
Sphingosine [D02.033.100.700]
Fingolimod Hydrochloride [D02.033.100.700.350]
Psychosine [D02.033.100.700.700]
Organic Chemicals [D02]
Alcohols [D02.033]
Glycols [D02.033.455]
Propylene Glycols [D02.033.455.706]
alpha-Chlorohydrin [D02.033.455.706.100]
Chloramphenicol [D02.033.455.706.300]
Chlorphenesin [D02.033.455.706.345]
Felbamate [D02.033.455.706.388]
Fingolimod Hydrochloride [D02.033.455.706.431]
Mephenesin [D02.033.455.706.517]
Pentaerythritol Tetranitrate [D02.033.455.706.690]
Propylene Glycol [D02.033.455.706.725]
Tromethamine [D02.033.455.706.900]
Organic Chemicals [D02]
Amines [D02.092]
Amino Alcohols [D02.092.063]
Sphingosine [D02.092.063.700]
Fingolimod Hydrochloride [D02.092.063.700.350]
Psychosine [D02.092.063.700.700]
Expand All
Collapse All
Fingolimod Hydrochloride
Preferred
Concept UI
M0259274
Registry Number
G926EC510T
Related Numbers
162359-56-0
3QN8BYN5QF
Scope Note
A sphingosine-derivative and
IMMUNOSUPPRESSIVE AGENT
that blocks the migration and homing of
LYMPHOCYTES
to the
CENTRAL NERVOUS SYSTEM
through its action on
SPHINGOSINE 1-PHOSPHATE RECEPTORS
. It is used in the treatment of
MULTIPLE SCLEROSIS
.
Terms
Fingolimod Hydrochloride
Preferred Term
Term UI
T000877612
Date
03/30/2015
LexicalTag
NON
ThesaurusID
2-Amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride
Term UI
T000877616
Date
03/30/2015
LexicalTag
NON
ThesaurusID
NLM (1996)
FTY-720
Narrower
Concept UI
M0521995
Registry Number
0
Terms
FTY-720
Preferred Term
Term UI
T289280
LexicalTag
LAB
ThesaurusID
NLM (1996)
FTY 720
Term UI
T289282
LexicalTag
LAB
ThesaurusID
NLM (1996)
FTY720
Term UI
T289281
LexicalTag
LAB
ThesaurusID
NLM (1996)
Gilenya
Narrower
Concept UI
M0587375
Registry Number
0
Terms
Gilenya
Preferred Term
Term UI
T848628
Date
08/30/2013
LexicalTag
TRD
ThesaurusID
NLM (2014)
Gilenia
Term UI
T000877613
Date
03/30/2015
LexicalTag
TRD
ThesaurusID
NLM (2016)
Fingolimod
Broader
Concept UI
M0259277
Registry Number
3QN8BYN5QF
Terms
Fingolimod
Preferred Term
Term UI
T000877611
Date
03/30/2015
LexicalTag
NON
ThesaurusID
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