ATP Binding Cassette Transporter, Subfamily G, Member 2 MeSH Descriptor Data 2024

MeSH Heading: ATP Binding Cassette Transporter, Subfamily G, Member 2
Tree Number(s): D09.400.430.890.020.457.500; D12.776.157.530.100.228.500; D12.776.395.550.020.457.500; D12.776.543.550.192.457.500; D12.776.543.585.100.228.500
Unique ID: D000070997
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000070997
Scope Note: ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.
Entry Term(s): ABCG2 Protein; ABCG2 Transporter; ATP Binding Cassette Transporter, Sub-Family G, Member 2; CD338 Antigen
Previous Indexing: ATP-Binding Cassette Transporters (1999-2016)
Public MeSH Note: 2019; see ATP BINDING CASSETTE TRANSPORTER, SUB-FAMILY G, MEMBER 2 2017-2018
History Note: 2019 (2017)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - ATP-Binding Cassette Transporters [D09.400.430.890.020]
        
        ATP Binding Cassette Transporter, Subfamily G [D09.400.430.890.020.457]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 1 [D09.400.430.890.020.457.250]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 2 [D09.400.430.890.020.457.500]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 5 [D09.400.430.890.020.457.750]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 8 [D09.400.430.890.020.457.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - ATP-Binding Cassette Transporters [D12.776.157.530.100]
        
        ATP Binding Cassette Transporter, Subfamily G [D12.776.157.530.100.228]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 1 [D12.776.157.530.100.228.250]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 2 [D12.776.157.530.100.228.500]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 5 [D12.776.157.530.100.228.750]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 8 [D12.776.157.530.100.228.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - ATP-Binding Cassette Transporters [D12.776.395.550.020]
        
        ATP Binding Cassette Transporter, Subfamily G [D12.776.395.550.020.457]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 1 [D12.776.395.550.020.457.250]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 2 [D12.776.395.550.020.457.500]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 5 [D12.776.395.550.020.457.750]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 8 [D12.776.395.550.020.457.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - ATP-Binding Cassette Transporters [D12.776.543.550.192]
        
        ATP Binding Cassette Transporter, Subfamily G [D12.776.543.550.192.457]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 1 [D12.776.543.550.192.457.250]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 2 [D12.776.543.550.192.457.500]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 5 [D12.776.543.550.192.457.750]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 8 [D12.776.543.550.192.457.875]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - ATP-Binding Cassette Transporters [D12.776.543.585.100]
        
        ATP Binding Cassette Transporter, Subfamily G [D12.776.543.585.100.228]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 1 [D12.776.543.585.100.228.250]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 2 [D12.776.543.585.100.228.500]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 5 [D12.776.543.585.100.228.750]
        
        ATP Binding Cassette Transporter, Subfamily G, Member 8 [D12.776.543.585.100.228.875]

ATP Binding Cassette Transporter, Subfamily G, Member 2 Preferred

Concept UI: M000612844
Scope Note: ATP-binding cassette transporter, sub-family G protein that functions as a high capacity UREA exporter, transporter of STEROLS, and in the absorption and efflux of many drugs. Its efflux activity for ANTINEOPLASTIC AGENTS contributes to DRUG RESISTANCE. It functions as a homodimer and is expressed by cells in a variety of organs, as well as by NEOPLASTIC STEM CELLS.
Terms: ATP Binding Cassette Transporter, Subfamily G, Member 2 Preferred Term
Term UI T000939222
Date01/16/2018
LexicalTag ABX
ThesaurusID NLM (2019); ABCG2 Protein
Term UI T000892300
Date12/18/2015
LexicalTag ABX
ThesaurusID NLM (2017); CD338 Antigen
Term UI T000892301
Date12/18/2015
LexicalTag ABX
ThesaurusID NLM (2017); ABCG2 Transporter
Term UI T000892326
Date12/18/2015
LexicalTag ABX
ThesaurusID NLM (2017); ATP Binding Cassette Transporter, Sub-Family G, Member 2
Term UI T000894710
Date02/05/2016
LexicalTag NON
ThesaurusID NLM (2017)

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