MeSH Browser

MeSH Heading: Influenza A Virus, H5N8 Subtype
Tree Number(s): B04.820.480.968.405.400.598
Unique ID: D000071225
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071225
Annotation: infection: coordinate with INFLUENZA, HUMAN in humans, or INFLUENZA IN BIRDS in birds, or ORTHOMYXOVIRIDAE INFECTIONS in other animals
Scope Note: A subtype of INFLUENZA A VIRUS that is highly virulent in poultry and wild birds, but shows varying degrees of pathogenicity in mice. The H5N8 virus subtype has a polybasic amino acid motif at the HA cleavage site which explains its pathogenicity in birds, and expresses surface proteins HEMAGGLUTININ 5 and NEURAMINIDASE 8 which are typical of Highly Pathogenic Avian Influenza viruses.
Entry Term(s): Avian Influenza A(H5N8) Virus; H5N8; H5N8 Bird Flu Virus; H5N8 Influenza Virus; H5N8 Virus; H5N8 subtype; Influenza A(H5N8) Virus
Registry Numbers: txid232441
Previous Indexing: Influenza A virus (2013-2016)
Public MeSH Note: 2017
History Note: 2017
Date Introduced: 2017/01/01
Last Updated: 2026/01/01

Allowable Qualifiers: chemistry (CH)

classification (CL)

drug effects (DE)

enzymology (EN)

genetics (GE)

growth & development (GD)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pathogenicity (PY)

physiology (PH)

radiation effects (RE)

ultrastructure (UL)

Viruses [B04]
- RNA Viruses [B04.820]
  - Negative-Sense RNA Viruses [B04.820.480]
    - Orthomyxoviridae [B04.820.480.968]
      - Alphainfluenzavirus [B04.820.480.968.405]
        
        Influenza A virus [B04.820.480.968.405.400]
        
        Influenza A Virus, H10N7 Subtype [B04.820.480.968.405.400.105]
        
        Influenza A Virus, H10N8 Subtype [B04.820.480.968.405.400.106]
        
        Influenza A Virus, H1N1 Subtype [B04.820.480.968.405.400.214]
        
        Influenza A Virus, H1N2 Subtype [B04.820.480.968.405.400.216]
        
        Influenza A Virus, H2N2 Subtype [B04.820.480.968.405.400.250]
        
        Influenza A Virus, H3N2 Subtype [B04.820.480.968.405.400.300]
        
        Influenza A Virus, H3N8 Subtype [B04.820.480.968.405.400.350]
        
        Influenza A Virus, H5N1 Subtype [B04.820.480.968.405.400.500]
        
        Influenza A Virus, H5N2 Subtype [B04.820.480.968.405.400.505]
        
        Influenza A Virus, H5N6 Subtype [B04.820.480.968.405.400.552]
        
        Influenza A Virus, H5N8 Subtype [B04.820.480.968.405.400.598]
        
        Influenza A Virus, H7N1 Subtype [B04.820.480.968.405.400.690]
        
        Influenza A Virus, H7N2 Subtype [B04.820.480.968.405.400.692]
        
        Influenza A Virus, H7N3 Subtype [B04.820.480.968.405.400.694]
        
        Influenza A Virus, H7N7 Subtype [B04.820.480.968.405.400.700]
        
        Influenza A Virus, H7N9 Subtype [B04.820.480.968.405.400.800]
        
        Influenza A Virus, H9N2 Subtype [B04.820.480.968.405.400.900]

Influenza A Virus, H5N8 Subtype Preferred

Concept UI: M000613668
Registry Numbers: txid232441
Scope Note: A subtype of INFLUENZA A VIRUS that is highly virulent in poultry and wild birds, but shows varying degrees of pathogenicity in mice. The H5N8 virus subtype has a polybasic amino acid motif at the HA cleavage site which explains its pathogenicity in birds, and expresses surface proteins HEMAGGLUTININ 5 and NEURAMINIDASE 8 which are typical of Highly Pathogenic Avian Influenza viruses.
Terms: Influenza A Virus, H5N8 Subtype Preferred Term
Term UI T000893876
Date01/20/2016
LexicalTag NON
ThesaurusID NLM (2017); Avian Influenza A(H5N8) Virus
Term UI T001147102
Date02/12/2025
LexicalTag NON
ThesaurusID NLM (2025); H5N8
Term UI T001147103
Date02/12/2025
LexicalTag NON
ThesaurusID NLM (2025); H5N8 Bird Flu Virus
Term UI T001147104
Date02/12/2025
LexicalTag NON
ThesaurusID NLM (2025); H5N8 Influenza Virus
Term UI T001147105
Date02/12/2025
LexicalTag NON
ThesaurusID NLM (2025); H5N8 subtype
Term UI T001133268
Date02/23/2023
LexicalTag ABX
ThesaurusID NLM (2024); H5N8 Virus
Term UI T000896268
Date03/01/2016
LexicalTag NON
ThesaurusID NLM (2017); Influenza A(H5N8) Virus
Term UI T001147106
Date02/12/2025
LexicalTag NON
ThesaurusID NLM (2025)

Influenza A Virus, H5N8 Subtype MeSH Descriptor Data 2026