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Histidine Kinase MeSH Descriptor Data 2022


MeSH Heading
Histidine Kinase
Tree Number(s)
D08.811.913.696.620.682.424
Unique ID
D000071677
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071677
Scope Note
A member of the transferase superfamily of proteins. In the activated state, protein-histidine kinase autophosphorylates at a histidine residue, subsequently transferring high-energy phosphoryl groups to an aspartate residue of the response-regulator domain, which results in a conformational shift in the effector domain. Histidine kinases mediate signal transduction in a wide range of processes involving cellular adaptation to environmental stress.
Entry Term(s)
Histidine Protein Kinase
Histone H4 Histidine Kinase
Protein Histidine Pros-Kinase
Protein Kinase (Histidine), Pros-Kinase
Protein-Histidine Kinase
Protein-Histidine Pros-Kinase
Protein-Histidine Tele-Kinase
Sensor Histidine Kinase
Registry Number
EC 2.7.13.1
Related Numbers
EC 2.7.13.1
EC 2.7.13.2
EC 2.7.13.3
Public MeSH Note
2017; PROTEIN-HISTIDINE KINASE was indexed under PROTEIN KINASES 1986-2016
History Note
2017 (1986)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2018/06/20
Histidine Kinase Preferred
Sensor Histidine Kinase Narrower
Protein-Histidine Tele-Kinase Narrower
Histone H4 Histidine Kinase Narrower
Protein Histidine Pros-Kinase Narrower
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