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Solute Carrier Family 22 Member 5 MeSH Descriptor Data 2025


MeSH Heading
Solute Carrier Family 22 Member 5
Tree Number(s)
D12.776.157.530.450.250.812.750
D12.776.157.530.937.612.750
D12.776.543.585.450.250.812.750
D12.776.543.585.937.701.750
Unique ID
D000074058
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074058
Scope Note
A high-affinity, ATP-binding, co-transporter for CARNITINE that is highly expressed in kidney, skeletal muscle, heart, and placental tissues. It transports one sodium ion with one carnitine molecule. It has a lower affinity for other organic cations and transports them independently of sodium. Mutations in the SLC22A5 gene are associated with systemic carnitine deficiency.
Entry Term(s)
High-Affinity Carnitine Transporter
OCTN2 Protein
Organic Cation-Carnitine Transporter 2
SLC22A5 Protein
Sodium-Dependent Carnitine Cotransporter
Registry Numbers
0
Previous Indexing
Carrier Proteins (1998-2017)
Organic Cation Transport Proteins (2004-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/03/31
Solute Carrier Family 22 Member 5 Preferred
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