MeSH Browser

MeSH Heading: Anastrozole
Tree Number(s): D02.626.218; D03.383.129.799.275
Unique ID: D000077384
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077384
Scope Note: A nitrile and triazole derivative that acts as a selective nonsteroidal aromatase inhibitor. It is used in the treatment of ESTROGEN NUCLEAR RECEPTOR-positive breast cancer in postmenopausal women.
Entry Term(s): 2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile); Anastrazole; Arimidex; ICI D1033; ZD-1033; ZD1033; Zeneca ZD 1033
Pharm Action: Antineoplastic Agents, Hormonal
Aromatase Inhibitors
Registry Numbers: 2Z07MYW1AZ; 0
Related Numbers: 120511-73-1
CAS Type 1 Name: 1,3-Benzenediacetonitrile, alpha,alpha,alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-
Public MeSH Note: 2019; ANASTROZOLE was indexed under NITRILES and TRIAZOLES 1994-2018
History Note: 2019 (1994)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/02/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0238999
Registry Numbers: 2Z07MYW1AZ
Related Numbers: 120511-73-1
Scope Note: A nitrile and triazole derivative that acts as a selective nonsteroidal aromatase inhibitor. It is used in the treatment of ESTROGEN NUCLEAR RECEPTOR-positive breast cancer in postmenopausal women.
Terms: Anastrozole Preferred Term
Term UI T000939550
Date01/23/2018
LexicalTag NON
ThesaurusID; 2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
Term UI T268999
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (1994); Anastrazole
Term UI T000939551
Date01/23/2018
LexicalTag NON
ThesaurusID NLM (2001)

Anastrozole MeSH Descriptor Data 2025