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Ivabradine MeSH Descriptor Data 2025


MeSH Heading
Ivabradine
Tree Number(s)
D03.633.100.079.801
Unique ID
D000077550
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077550
Scope Note
A benzazepine derivative and selective HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS inhibitor that lowers the heart rate. It is used in the treatment of CHRONIC STABLE ANGINA in patients unable to take BETA-ADRENERGIC BLOCKERS, and in the treatment of HEART FAILURE.
Entry Term(s)
7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one
Corlanor
S 16257
S 16257-2
S 16260-2
S-16257
S-16257-2
S-16260-2
Pharm Action
Cardiovascular Agents
Registry Numbers
3H48L0LPZQ
0
Related Numbers
155974-00-8
CAS Type 1 Name
2H-3-Benzazepin-2-one, 3-(3-((((7S)-3,4-dimethoxybicyclo(4.2.0)octa-1,3,5-trien-7-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-7,8-dimethoxy-
Public MeSH Note
2019; IVABRADINE was indexed under BENZAZEPINES 1994-2018
History Note
2019 (1994)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/06/20
Ivabradine Preferred
S 16257 Narrower
S 16257-2 Narrower
Corlanor Narrower
7,8-Dimethoxy-3-(3-(((4,5-dimethoxybenzocyclobutan-1-yl)methyl)methylamino)propyl)-1,3,4,5-tetrahydro-2H-benzazepin-2-one Narrower
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