MeSH Browser

MeSH Heading: O-(Chloroacetylcarbamoyl)fumagillol
Tree Number(s): D02.455.426.392.368.367.763; D02.455.849.765.597
Unique ID: D000077609
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000077609
Scope Note: Semisynthetic analog of fumagillin (a cyclohexane-sesquiterpene antibiotic isolated from ASPERGILLUS FUMIGATUS) that inhibits angiogenesis.
Entry Term(s): 5-Methoxy-4-(2-methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2,5)oct-6-yl(chloroacetyl) carbamate; AGM 1470; AGM-1470; Caplostatin; TNP 470; TNP-470
Pharm Action: Antibiotics, Antineoplastic
Angiogenesis Inhibitors
Registry Numbers: X47GR46481; 0
Related Numbers: 129298-91-5
Public MeSH Note: 2019; O-(CHLOROACETYLCARBAMOYL)FUMAGILLOL was indexed under CYCLOHEXANES and SESQUITERPENES 1991-2018
History Note: 2019 (1991)
Date Established: 2019/01/01
Date of Entry: 2018/07/09
Revision Date: 2018/04/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

O-(Chloroacetylcarbamoyl)fumagillol MeSH Descriptor Data 2025