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Amifampridine MeSH Descriptor Data 2022


MeSH Heading
Amifampridine
Tree Number(s)
D02.092.080.060.500
D03.383.725.050.060.500
Unique ID
D000077770
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077770
Scope Note
4-Aminopyridine derivative that acts as a POTASSIUM CHANNEL blocker to increase release of ACETYLCHOLINE from nerve terminals. It is used in the treatment of CONGENITAL MYASTHENIC SYNDROMES.
Entry Term(s)
3,4-Diaminopyridine
Amifampridine Phosphate
Firdapse
Ruzurgi
Pharm Action
Neuromuscular Agents
Potassium Channel Blockers
Registry Number
RU4S6E2G0J
Related Numbers
54-96-6
8HF8FIN815
CAS Type 1 Name
3,4-Pyridinediamine
Public MeSH Note
2019; see 3,4-DIAMINOPYRIDINE 1978-2018; AMIFAMPRIDINE was indexed under 4-AMINOPYRIDINE/analogs & derivatives 1990-2018; under AMINOPYRIDINES 1978-1989; and under PYRIDINES 1978-1979
History Note
2019 (1978)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2019/07/05
Amifampridine Preferred
Firdapse Narrower
Ruzurgi Narrower
Amifampridine Phosphate Narrower
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