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Atrasentan MeSH Descriptor Data 2022


MeSH Heading
Atrasentan
Tree Number(s)
D03.383.246.118.300
D03.383.773.079
D03.633.100.115.300
Unique ID
D000077868
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077868
Scope Note
A pyrrolidine and benzodioxole derivative that acts a RECEPTOR, ENDOTHELIN A antagonist. It has therapeutic potential as an antineoplastic agent and for the treatment of DIABETIC NEPHROPATHIES.
Entry Term(s)
(11C)ABT-627
2-(4-Methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-(((dibutylamino)carbonyl)methyl)pyrrolidine-3-carboxylic acid
A 127722
A 147627
A-127722
A-127722.5
A-147627
ABT 627
ABT-627
Atrasentan Hydrochloride
Xinlay
Pharm Action
Antineoplastic Agents
Endothelin A Receptor Antagonists
Registry Number
V6D7VK2215
Related Numbers
E4G31X93ZA
CAS Type 1 Name
3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)-, (2R,3R,4S)-
Public MeSH Note
2019; ATRASENTAN was indexed under PYRROLIDINES 1996-2018
History Note
2019 (1996)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2018/05/21
Atrasentan Preferred
A 127722 Narrower
Atrasentan Hydrochloride Narrower
A 147627 Narrower
ABT 627 Narrower
2-(4-Methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-(((dibutylamino)carbonyl)methyl)pyrrolidine-3-carboxylic acid Broader
(11C)ABT-627 Narrower
Xinlay Narrower
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