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Phase Variation MeSH Descriptor Data 2025


MeSH Heading
Phase Variation
Tree Number(s)
G05.365.693
Unique ID
D000090502
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000090502
Scope Note
An adaptive mechanism used by microbes to avoid detection by the host or adapt to changes in environment by randomly and rapidly switch on and off of a gene by various mechanisms between on and off phases. For instance, drug tolerant MYCOBACTERIUM TUBERCULOSIS arises through rapid reversible mutations in the glpK gene through phase variation.
Entry Term(s)
Phase-Variable Regulons
Phasevarions
Public MeSH Note
2022
History Note
2022
Date Established
2022/01/01
Date of Entry
2021/07/09
Revision Date
2022/04/29
Phase Variation Preferred
Phasevarions Related
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