MeSH Browser

MeSH Heading: Delta-5 Fatty Acid Desaturase
Tree Number(s): D08.811.682.690.708.392.390
Unique ID: D000090943
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000090943
Scope Note: A fatty acid desaturase that is a rate-limiting enzyme for the conversion from dihomo-gamma-linolenic acid and EICOSATETRAENOATE (ETA) in the synthesis of ARACHIDONIC ACID and EICOSAPENTAENOATE (EPA). It is also involved in the biosynthesis of unsaturated fatty acids from the polyunsaturated fatty acids (PUFA), LINOLEIC ACID (LA), and ALPHA LINOLENIC ACID (ALA) precursors and plays an important role in the metabolism of inflammatory lipids including PROSTAGLANDIN E2.
Entry Term(s): Delta 5 Desaturase; Delta-5-FADase; Fatty Acid Delta-5-Desaturase
Registry Number: 0
Related Numbers: EC 1.14.19.3; EC 1.14.99.-
Public MeSH Note: 2022; DELTA-5 FATTY ACID DESATURASE was indexed under FATTY ACID DESATURASES 1982-2021
History Note: 2022 (1981)
Date Established: 2022/01/01
Date of Entry: 2021/07/09
Revision Date: 2021/06/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000747567
Registry Number: 0
Related Numbers: EC 1.14.19.3; EC 1.14.99.-
Scope Note: A fatty acid desaturase that is a rate-limiting enzyme for the conversion from dihomo-gamma-linolenic acid and EICOSATETRAENOATE (ETA) in the synthesis of ARACHIDONIC ACID and EICOSAPENTAENOATE (EPA). It is also involved in the biosynthesis of unsaturated fatty acids from the polyunsaturated fatty acids (PUFA), LINOLEIC ACID (LA), and ALPHA LINOLENIC ACID (ALA) precursors and plays an important role in the metabolism of inflammatory lipids including PROSTAGLANDIN E2.
Terms: Delta-5 Fatty Acid Desaturase Preferred Term
Term UI T001105748
Date04/30/2021
LexicalTag NON
ThesaurusID NLM (2022); Fatty Acid Delta-5-Desaturase
Term UI T001105751
Date04/30/2021
LexicalTag NON
ThesaurusID NLM (2022); Delta-5-FADase
Term UI T001105750
Date04/30/2021
LexicalTag NON
ThesaurusID NLM (2022); Delta 5 Desaturase
Term UI T001105749
Date04/30/2021
LexicalTag NON
ThesaurusID NLM (2022)

Delta-5 Fatty Acid Desaturase MeSH Descriptor Data 2024