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Mitogen-Activated Protein Kinase Kinase Kinase 11 MeSH Descriptor Data 2025
A MAP kinase kinase kinase that activates the SAPK/JNK and p38/ERK SIGNAL TRANSDUCTION pathways. It has multiple interaction domains, including a Cdc42 binding motif.
Entry Term(s)
Mixed Lineage Kinase 3
Mixed Lineage Kinase-3
Registry Numbers
EC 2.7.11.25
Public MeSH Note
2024: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11 was indexed under MAP KINASE KINASE KINASES 2000-2023, and under PROTEIN-SERINE-THREONINE KINASES 1997-1999
A MAP kinase kinase kinase that activates the SAPK/JNK and p38/ERK SIGNAL TRANSDUCTION pathways. It has multiple interaction domains, including a Cdc42 binding motif.