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Mitogen-Activated Protein Kinase Kinase Kinase 11 MeSH Descriptor Data 2025


MeSH Heading
Mitogen-Activated Protein Kinase Kinase Kinase 11
Tree Number(s)
D08.811.913.696.620.682.700.559.650
D12.776.476.563.554.650
Unique ID
D000097767
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000097767
Scope Note
A MAP kinase kinase kinase that activates the SAPK/JNK and p38/ERK SIGNAL TRANSDUCTION pathways. It has multiple interaction domains, including a Cdc42 binding motif.
Entry Term(s)
Mixed Lineage Kinase 3
Mixed Lineage Kinase-3
Registry Numbers
EC 2.7.11.25
Public MeSH Note
2024: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11 was indexed under MAP KINASE KINASE KINASES 2000-2023, and under PROTEIN-SERINE-THREONINE KINASES 1997-1999
History Note
2024 (1997)
Date Established
2024/01/01
Date of Entry
2023/07/26
Revision Date
2023/06/14
Mitogen-Activated Protein Kinase Kinase Kinase 11 Preferred
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