MeSH Browser

MeSH Heading: T-bet Transcription Factor
Tree Number(s): D12.776.260.725.500
Unique ID: D000098815
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000098815
Scope Note: A transcription factor of the T-box family of transcription factors, functions in immune system regulation, particularly in T-cell differentiation. It also is involved in the development of Th1 cells and the regulation of CXCR3 expression.
Entry Term(s): T-box Transcription Factor; T-box Transcription Factor TBX21; Transcription Factor TBLYM
Registry Numbers: 0
Public MeSH Note: 2025; T-BOX TRANSCRIPTION FACTOR was indexed under T-BOX DOMAIN PROTEINS 2000-2024
History Note: 2025 (2000)
Date Established: 2025/01/01
Date of Entry: 2024/08/09
Revision Date: 2024/03/06

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000767379
Registry Numbers: 0
Scope Note: A transcription factor of the T-box family of transcription factors, functions in immune system regulation, particularly in T-cell differentiation. It also is involved in the development of Th1 cells and the regulation of CXCR3 expression.
Terms: T-bet Transcription Factor Preferred Term
Term UI T001142926
Date02/16/2024
LexicalTag NON
ThesaurusID NLM (2025); Transcription Factor TBLYM
Term UI T001142925
Date02/16/2024
LexicalTag NON
ThesaurusID NLM (2025); T-box Transcription Factor TBX21
Term UI T001142927
Date02/16/2024
LexicalTag NON
ThesaurusID NLM (2025); T-box Transcription Factor
Term UI T001142924
Date02/16/2024
LexicalTag NON
ThesaurusID NLM (2025)

T-bet Transcription Factor MeSH Descriptor Data 2025