MeSH Browser

MeSH Heading: Adenylyl Imidodiphosphate
Tree Number(s): D03.633.100.759.646.138.236.050; D13.695.667.138.236.050; D13.695.827.068.236.050
Unique ID: D000266
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000266
Scope Note: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation.
Entry Version: APPNHP
Entry Term(s): AMP-PNP; AMPPNP; ATP(beta,gamma-NH); Adenosine 5'-(beta,gamma-Imino)triphosphate; Adenyl Imidodiphosphate; Adenylimidodiphosphate; Adenylylimidodiphosphate; Mg AMP-PNP; Mg-5'-Adenylylimidodiphosphate; beta,gamma-imido-ATP; gamma-Imido-ATP; gamma-Imino-ATP
Registry Numbers: 25612-73-1; 0
CAS Type 1 Name: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid
Previous Indexing: Adenosine Diphosphate (1973-1974); Adenosine Triphosphate/analogs & derivatives (1975); Imides (1973-1975); Phosphoric Acids (1973-1974)
Public MeSH Note: 91; was see under ADENOSINE TRIPHOSPHATE 1976-90
History Note: 91(76); was see under ADENOSINE TRIPHOSPHATE 1976-90
Date Established: 1991/01/01
Date of Entry: 1975/07/23
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Purines [D03.633.100.759]
      - Purine Nucleotides [D03.633.100.759.646]
        
        Adenine Nucleotides [D03.633.100.759.646.138]
        
        Adenosine Triphosphate [D03.633.100.759.646.138.236]
        
        Adenylyl Imidodiphosphate [D03.633.100.759.646.138.236.050]
        
        Ethenoadenosine Triphosphate [D03.633.100.759.646.138.236.250]

Nucleic Acids, Nucleotides, and Nucleosides [D13]
- Nucleotides [D13.695]
  - Purine Nucleotides [D13.695.667]
    - Adenine Nucleotides [D13.695.667.138]
      - Adenosine Triphosphate [D13.695.667.138.236]
        
        Adenylyl Imidodiphosphate [D13.695.667.138.236.050]
        
        Ethenoadenosine Triphosphate [D13.695.667.138.236.250]

Nucleic Acids, Nucleotides, and Nucleosides [D13]
- Nucleotides [D13.695]
  - Ribonucleotides [D13.695.827]
    - Adenine Nucleotides [D13.695.827.068]
      - Adenosine Triphosphate [D13.695.827.068.236]
        
        Adenylyl Imidodiphosphate [D13.695.827.068.236.050]
        
        Ethenoadenosine Triphosphate [D13.695.827.068.236.250]

Adenylyl Imidodiphosphate Preferred

Concept UI: M0000416
Registry Numbers: 25612-73-1
Scope Note: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation.
Terms: Adenylyl Imidodiphosphate Preferred Term
Term UI T000835
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1976); AMPPNP
Term UI T000836
Date08/18/1980
LexicalTag ABB
ThesaurusID UNK (19XX); ATP(beta,gamma-NH)
Term UI T000837
Date11/23/1982
LexicalTag NON
ThesaurusID UNK (19XX); beta,gamma-imido-ATP
Term UI T000838
Date11/23/1982
LexicalTag NON
ThesaurusID UNK (19XX); gamma-Imido-ATP
Term UI T000839
Date08/21/1980
LexicalTag NON
ThesaurusID UNK (19XX); gamma-Imino-ATP
Term UI T000840
Date06/30/1975
LexicalTag NON
ThesaurusID UNK (19XX); Adenyl Imidodiphosphate
Term UI T000841
Date06/30/1975
LexicalTag NON
ThesaurusID UNK (19XX); Adenylimidodiphosphate
Term UI T000842
Date08/18/1980
LexicalTag NON
ThesaurusID UNK (19XX); Adenylylimidodiphosphate
Term UI T000843
Date08/18/1980
LexicalTag NON
ThesaurusID UNK (19XX); Adenosine 5'-(beta,gamma-Imino)triphosphate
Term UI T000834
Date07/31/1980
LexicalTag NON
ThesaurusID UNK (19XX); AMP-PNP
Term UI T000844
Date08/01/1980
LexicalTag ABB
ThesaurusID UNK (19XX)

Mg-5'-Adenylylimidodiphosphate Narrower

Adenylyl Imidodiphosphate MeSH Descriptor Data 2025