MeSH Browser

MeSH Heading: Adjuvants, Immunologic
Tree Number(s): D27.505.696.477.067
Unique ID: D000276
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000276
Scope Note: Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Entry Version: ADJUVANTS IMMUNOL
Entry Term(s): Adjuvant, Immunologic; Adjuvants, Immunological; Immunoactivators; Immunoadjuvant; Immunoadjuvants; Immunologic Adjuvant; Immunologic Adjuvants; Immunological Adjuvant; Immunopotentiator; Immunopotentiators; Immunostimulant; Immunostimulants
NLM Classification #: QW 800
See Also: Adjuvants, Pharmaceutic
Public MeSH Note: 65
History Note: 65
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

economics (EC)

genetics (GE)

history (HI)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Physiological Effects of Drugs [D27.505.696]
    - Immunologic Factors [D27.505.696.477]

Adjuvants, Immunologic Preferred

Concept UI: M0000431
Scope Note: Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.
Terms: Adjuvants, Immunologic Preferred Term
Term UI T000868
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1965); Immunostimulant
Term UI T000996501
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); Immunologic Adjuvant
Term UI T001007237
Date02/10/2020
LexicalTag NON
ThesaurusID NLM (2021); Immunopotentiator
Term UI T001007238
Date02/10/2020
LexicalTag NON
ThesaurusID NLM (2021); Immunopotentiators
Term UI T000872
Date12/15/1978
LexicalTag NON
ThesaurusID UNK (19XX); Immunostimulants
Term UI T000873
Date12/15/1978
LexicalTag NON
ThesaurusID UNK (19XX); Adjuvant, Immunologic
Term UI T000866
Date10/02/1990
LexicalTag NON
ThesaurusID NLM (1992); Adjuvants, Immunological
Term UI T000874
Date06/26/1978
LexicalTag NON
ThesaurusID UNK (19XX); Immunoactivators
Term UI T000869
Date12/15/1978
LexicalTag NON
ThesaurusID UNK (19XX); Immunoadjuvants
Term UI T000870
Date12/15/1978
LexicalTag NON
ThesaurusID UNK (19XX); Immunologic Adjuvants
Term UI T000867
Date07/29/1988
LexicalTag NON
ThesaurusID UNK (19XX); Immunoadjuvant
Term UI T001007236
Date02/10/2020
LexicalTag NON
ThesaurusID NLM (2021); Immunological Adjuvant
Term UI T000875
Date01/27/1993
LexicalTag NON
ThesaurusID NLM (1994)

Adjuvants, Immunologic MeSH Descriptor Data 2024