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Eflornithine MeSH Descriptor Data 2022


MeSH Heading
Eflornithine
Tree Number(s)
D12.125.068.665.340
D12.125.095.765.340
Unique ID
D000518
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000518
Scope Note
An inhibitor of ORNITHINE DECARBOXYLASE, the rate limiting enzyme of the polyamine biosynthetic pathway.
Entry Term(s)
DL-alpha-Difluoromethylornithine
Difluoromethylornithine
Eflornithine Hydrochloride
Eflornithine Monohydrochloride, Monohydrate
MDL-71,782 A
Ornidyl
RMI 71782
Vaniqa
alpha-Difluoromethyl Ornithine
alpha-Difluoromethylornithine
Pharm Action
Antineoplastic Agents
Trypanocidal Agents
Ornithine Decarboxylase Inhibitors
Registry Number
ZQN1G5V6SR
Related Numbers
4NH22NDW9H
67037-37-0
70052-12-9
96020-91-6
CAS Type 1 Name
Ornithine, 2-(difluoromethyl)-
Previous Indexing
Ornithine (1966-1974)
Ornithine/analogs & derivatives (1975-1986)
Public MeSH Note
1991; see ALPHA-DIFLUOROMETHYLORNITHINE 1987-1990
History Note
1991; use ALPHA-DIFLUOROMETHYLORNITHINE 1987-1990
Date Established
1987/01/01
Date of Entry
1986/06/03
Revision Date
2018/05/21
Eflornithine Preferred
MDL-71,782 A Narrower
Ornidyl Narrower
Vaniqa Narrower
Eflornithine Monohydrochloride, Monohydrate Narrower
Eflornithine Hydrochloride Narrower
RMI 71782 Narrower
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