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alpha-MSH MeSH Descriptor Data 2022


MeSH Heading
alpha-MSH
Tree Number(s)
D06.472.699.327.935.179
D06.472.699.327.935.531.750.050
D06.472.699.631.525.600.179
D06.472.699.631.525.600.531.750.050
D12.644.400.400.935.179
D12.644.400.400.935.531.750.050
D12.644.400.460.050
D12.644.548.365.935.179
D12.644.548.365.935.531.750.050
D12.644.548.691.525.690.179
D12.644.548.691.525.690.531.750.050
D12.776.631.650.405.935.179
D12.776.631.650.405.935.531.750.050
D12.776.631.650.460.050
Unique ID
D000521
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000521
Scope Note
A 13-amino acid peptide derived from proteolytic cleavage of ADRENOCORTICOTROPIC HORMONE, the N-terminal segment of ACTH. ACTH (1-13) is amidated at the C-terminal to form ACTH (1-13)NH2 which in turn is acetylated to form alpha-MSH in the secretory granules. Alpha-MSH stimulates the synthesis and distribution of MELANIN in MELANOCYTES in mammals and MELANOPHORES in lower vertebrates.
Entry Term(s)
(Des-Acetyl)-alpha-MSH
(Desacetyl)alpha-MSH
ACTH (1-13)
ACTH (1-13)NH2
ACTH(1-13)
Acetylated ACTH (1-13)NH2
Adrenocorticotropin (1-13)NH2
DE-alpha-MSH
Des-Acetyl MSH
Desacetyl alpha-MSH
Desacetyl alpha-Melanocyte-Stimulating Hormone
MSH, (Desacetyl)alpha-
MSH, alpha
alpha Intermedin
alpha-Melanocyte-Stimulating Hormone
alpha-Melanotropin
Pharm Action
Hormones
Registry Number
581-05-5
CAS Type 1 Name
alpha-Melanotropin
Previous Indexing
MSH (1966-1987)
Public MeSH Note
1988; ACTH (1-13) was indexed under PEPTIDE FRAGMENTS & ALPHA-MSH 1981-2006
History Note
1988 (1981)
Date Established
1988/01/01
Date of Entry
1987/05/05
Revision Date
2019/04/29
alpha-MSH Preferred
ACTH (1-13)NH2 Narrower
ACTH (1-13) Narrower
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