MeSH Browser

MeSH Heading: Amantadine
Tree Number(s): D02.455.426.100.050.035
Unique ID: D000547
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000547
Scope Note: An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Entry Term(s): 1-Aminoadamantane; Adamantylamine; Adekin; Aman; Amanta; Amanta-HCI-AZU; Amanta-Sulfate-AZU; Amantadin AL; Amantadin AZU; Amantadin Stada; Amantadin-neuraxpharm; Amantadin-ratiopharm; Amantadina Juventus; Amantadina Llorente; Amantadine Hydrochloride; Amantadine Sulfate; Amixx; Cerebramed; Endantadine; Gen-Amantadine; Infecto-Flu; Infex; Mantadix; Midantan; PMS-Amantadine; Symadine; Symmetrel; Viregyt; Wiregyt; tregor
Pharm Action: Antiparkinson Agents
Antiviral Agents
Dopamine Agents
Analgesics, Non-Narcotic
Related Numbers: 665-66-7; 768-94-5; 9921T5P019; M6Q1EO9TD0
CAS Type 1 Name: Tricyclo(3.3.1.13,7)decan-1-amine
Public MeSH Note: 68
History Note: 68(65)
Date Established: 1968/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0000847
Related Numbers: 665-66-7; 768-94-5; 9921T5P019; M6Q1EO9TD0
Scope Note: An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
Terms: Amantadine Preferred Term
Term UI T001662
Date01/01/1999
LexicalTag NON
ThesaurusID; 1-Aminoadamantane
Term UI T001660
Date10/23/1981
LexicalTag NON
ThesaurusID UNK (19XX); Adamantylamine
Term UI T001661
Date08/25/1980
LexicalTag NON
ThesaurusID UNK (19XX)