MeSH Browser

MeSH Heading: Amphetamine
Tree Number(s): D02.092.471.683.152.110
Unique ID: D000661
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000661
Annotation: a specific chem: do not confuse with AMPHETAMINES; d-amphetamine = DEXTROAMPHETAMINE; N-methylamphetamine = METHAMPHETAMINE
Scope Note: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
Entry Term(s): Amfetamine; Amphetamine Sulfate; Amphetamine Sulfate (2:1); Centramina; Desoxynorephedrin; Fenamine; Levoamphetamine; Mydrial; Phenamine; Phenopromin; Thyramine; l-Amphetamine; levo-Amphetamine
Pharm Action: Central Nervous System Stimulants
Sympathomimetics
Dopamine Agents
Adrenergic Agents
Adrenergic Uptake Inhibitors
Dopamine Uptake Inhibitors
Related Numbers: 300-62-9; 60-13-9; 60-15-1; 6DPV8NK46S
CAS Type 1 Name: Benzeneethanamine, alpha-methyl-, (+-)-
Entry Combination: analogs & derivatives:Amphetamines
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05

Entry Combination: analogs & derivatives:Amphetamines
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0001012
Related Numbers: 300-62-9; 60-13-9; 60-15-1; 6DPV8NK46S
Scope Note: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.
Terms: Amphetamine Preferred Term
Term UI T001988
Date01/01/1999
LexicalTag NON
ThesaurusID BAN (19XX); Desoxynorephedrin
Term UI T001989
Date12/30/1976
LexicalTag NON
ThesaurusID UNK (19XX); Phenamine
Term UI T001992
Date08/04/1980
LexicalTag NON
ThesaurusID UNK (19XX); Phenopromin
Term UI T001993
Date12/30/1976
LexicalTag NON
ThesaurusID UNK (19XX); Amfetamine
Term UI T001995
Date08/11/1994
LexicalTag NON
ThesaurusID INN (19XX)

Amphetamine MeSH Descriptor Data 2024