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GTP Pyrophosphokinase MeSH Descriptor Data 2025


MeSH Heading
GTP Pyrophosphokinase
Tree Number(s)
D08.811.913.696.175.300
Unique ID
D001277
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001277
Scope Note
An enzyme that catalyzes reversibly the transfer of a pyrophosphate group from ATP to the 3'-OH group of GDP or GTP with the formation of guanosine 3'-diphosphate 5'-diphosphate or guanosine 3'-diphosphate 5'-triphosphate and AMP. The enzyme, also called stringent factor, is located in the relA gene in stringent strains of bacteria. The above synthesis is induced by mRNA and uncharged tRNA which is bound to the aminoacyl-t-RNA binding site of the ribosome by a codon-specific association. EC 2.7.6.5.
Entry Term(s)
ATP-Guanosine Phosphate Pyrophosphotransferase
Stringent Factor
Registry Numbers
EC 2.7.6.5
Related Numbers
63690-89-1
CAS Type 1 Name
ATP:GTP 3'-pyrophosphotransferase
Previous Indexing
Adenosine Triphosphate (1966-1979)
Bacterial Proteins (1966-1979)
Guanine Nucleotides (1966-1979)
Phosphotransferases (1966-1973)
Phosphotransferases, ATP (1974-1979)
Pyrophosphates (1966-1979)
Ribosomal Proteins (1975-1979)
Public MeSH Note
92; was ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91 (see under PHOSPHOTRANSFERASES, ATP 1980-90)
Online Note
use GTP PYROPHOSPHOKINASE to search ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91
History Note
92; was ATP-GUANOSINE PHOSPHATE PYROPHOSPHOTRANSFERASE 1980-91 (see under PHOSPHOTRANSFERASES, ATP 1980-90)
Date Established
1991/01/01
Date of Entry
1979/05/23
Revision Date
2003/07/09
GTP Pyrophosphokinase Preferred
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