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Autophagy MeSH Descriptor Data 2022


MeSH Heading
Autophagy
Tree Number(s)
G04.011
Unique ID
D001343
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D001343
Annotation
general or unspecified; note specifics; do not confuse with AUTOPHAGIC CELL DEATH, a form of regulated cell death
Scope Note
The segregation and degradation of various cytoplasmic constituents via engulfment by MULTIVESICULAR BODIES; VACUOLES; or AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
Entry Term(s)
Autophagocytosis
Autophagy, Cellular
ER-Phagy
Lipophagy
Nucleophagy
Reticulophagy
Ribophagy
NLM Classification #
QU 375
Previous Indexing
Autolysis (1968-1978)
Lysosomes (1966-1978)
Phagocytosis (1966-1978)
Public MeSH Note
2006; see AUTOPHAGOCYTOSIS 1991-2005, PHAGOCYTOSIS 1979-1990
History Note
2006(1979)
Date Established
1991/01/01
Date of Entry
1978/03/20
Revision Date
2019/07/05
Autophagy Preferred
Reticulophagy Broader
Nucleophagy Narrower
Ribophagy Narrower
Lipophagy Narrower
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