MeSH Browser

MeSH Heading: Bicuculline
Tree Number(s): D03.132.098.077; D03.633.100.531.085.077
Unique ID: D001640
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D001640
Scope Note: An isoquinoline alkaloid obtained from Dicentra cucullaria and other plants. It is a competitive antagonist for GABA-A receptors.
Entry Term(s): 6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)furo(3,4-e)1,3-benzodioxol-8(6H)one
Pharm Action: Convulsants
GABA-A Receptor Antagonists
Related Numbers: 485-49-4
CAS Type 1 Name: Furo(3,4-e)-1,3-benzodioxol-8(6H)-one, 6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (R-(R*,S*))-
NLM Classification #: QV 103
Previous Indexing: Alkaloids (1972-1974); Dioxoles (1972-1974); Isoquinolines (1971-1974)
Public MeSH Note: 80; was see under ISOQUINOLINES 1975-79
History Note: 80(75); was see under ISOQUINOLINES 1975-79
Date Established: 1980/01/01
Date of Entry: 1974/11/11
Revision Date: 2016/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

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analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

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chemistry (CH)

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poisoning (PO)

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therapeutic use (TU)

toxicity (TO)

urine (UR)

Bicuculline MeSH Descriptor Data 2024