MeSH Browser

MeSH Heading: Clofazimine
Tree Number(s): D03.633.300.704.353
Unique ID: D002991
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D002991
Scope Note: A fat-soluble riminophenazine dye used for the treatment of leprosy. It has been used investigationally in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in AIDS patients. Clofazimine also has a marked anti-inflammatory effect and is given to control the leprosy reaction, erythema nodosum leprosum. (From AMA Drug Evaluations Annual, 1993, p1619)
Entry Term(s): B-663; G-30,320; Lamprene; N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-2-phenazinamine
Pharm Action: Anti-Inflammatory Agents
Leprostatic Agents
Registry Numbers: D959AE5USF; 0
Related Numbers: 2030-63-9
CAS Type 1 Name: 2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)-
Public MeSH Note: 74
History Note: 74
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Clofazimine MeSH Descriptor Data 2025