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Dextromethorphan MeSH Descriptor Data 2022


MeSH Heading
Dextromethorphan
Tree Number(s)
D03.132.577.249.200
D03.605.497.212
D03.633.400.686.212
D04.615.723.795.200
Unique ID
D003915
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D003915
Scope Note
Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
Entry Term(s)
Delsym
Dextromethorphan Hydrobromide
Dextromethorphan Hydrobromide, (+-)-Isomer
Dextromethorphan Hydrobromide, Monohydrate
Dextromethorphan Hydrochloride
Dextromethorphan, (+-)-Isomer
Levomethorphan
Racemethorphan
d-Methorphan
l-Methorphan
Pharm Action
Antitussive Agents
Excitatory Amino Acid Antagonists
Registry Number
7355X3ROTS
Related Numbers
125-68-8
125-69-9
125-71-3
18609-21-7
351KFH969D
510-53-2
6031-86-3
6700-34-1
7ZZ22K9QE6
8YB8F78WM1
9D2RTI9KYH
CAS Type 1 Name
Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-
Previous Indexing
Antitussive Agents (1966-1971)
Morphinans (1969-1971)
Public MeSH Note
91; was see under LEVORPHANOL 1972-90
History Note
91(72); was see under LEVORPHANOL 1972-90
Date Established
1991/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/29
Dextromethorphan Preferred
Dextromethorphan, (+-)-Isomer Related
l-Methorphan Related
Levomethorphan Related
Dextromethorphan Hydrobromide, Monohydrate Narrower
Delsym Narrower
Dextromethorphan Hydrobromide Narrower
Dextromethorphan Hydrobromide, (+-)-Isomer Related
Dextromethorphan Hydrochloride Narrower
Racemethorphan Broader
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