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Disulfiram MeSH Descriptor Data 2022


MeSH Heading
Disulfiram
Tree Number(s)
D02.241.081.251.869.220.250
D02.886.520.150.175
D02.886.706.200.200
Unique ID
D004221
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004221
Scope Note
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
Entry Term(s)
Alcophobin
Antabus
Antabuse
Anticol
Bis(diethylthiocarbamoyl) Disulfide
Dicupral
Esperal
Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2
Tetraethylthiuram Disulfide
Teturam
Pharm Action
Alcohol Deterrents
Acetaldehyde Dehydrogenase Inhibitors
Registry Number
TR3MLJ1UAI
Related Numbers
97-77-8
CAS Type 1 Name
Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl-
Date Established
1966/01/01
Date of Entry
1999/01/01
Revision Date
2016/07/05
Disulfiram Preferred
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