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Amifostine MeSH Descriptor Data 2024


MeSH Heading
Amifostine
Tree Number(s)
D02.705.400.625.050
D02.705.539.345.050
D02.886.300.692.050
Unique ID
D004999
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004999
Scope Note
A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Entry Term(s)
APAETP
Amifostine Anhydrous
Amifostine Disodium Salt
Amifostine Monohydrate
Amifostine Monohydrochloride
Amifostine Trihydrate
Aminopropyl Aminoethylthiophosphate
Aminopropylaminoethylthiophosphate
Aminopropylaminoethylthiophosphoric Acid
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Ethiofos
Ethiofos Anhydrous
Ethyol
Gammaphos
NSC-296961
S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid
WR-2721
YM-08310
Pharm Action
Radiation-Protective Agents
Registry Number
M487QF2F4V
Related Numbers
104087-08-3
20537-88-6
59178-37-9
63717-27-1
ILA426L95O
L693H6MM64
CAS Type 1 Name
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester)
Previous Indexing
Diamines (1974-1976)
Organothiophosphorus Compounds (1972-1976)
Public MeSH Note
1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984
Online Note
use AMIFOSTINE to search ETHIOFOS 1985-93 & WR 2721 1977-84
History Note
1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984
Date Established
1991/01/01
Date of Entry
1976/04/13
Revision Date
2018/05/30
Amifostine Preferred
Aminopropylaminoethylthiophosphoric Acid Broader
Gammaphos Narrower
Ethiofos Narrower
Amifostine Disodium Salt Narrower
Amifostine Monohydrate Narrower
Amifostine Trihydrate Narrower
Aminopropylaminoethylthiophosphate Narrower
Ethyol Narrower
NSC-296961 Narrower
Amifostine Anhydrous Narrower
WR-2721 Narrower
YM-08310 Narrower
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate Narrower
Amifostine Monohydrochloride Narrower
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