MeSH Browser

MeSH Heading: Formate Dehydrogenases
Tree Number(s): D08.811.682.657.180
Unique ID: D005560
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005560
Scope Note: Flavoproteins that catalyze reversibly the reduction of carbon dioxide to formate. Many compounds can act as acceptors, but the only physiologically active acceptor is NAD. The enzymes are active in the fermentation of sugars and other compounds to carbon dioxide and are the key enzymes in obtaining energy when bacteria are grown on formate as the main carbon source. They have been purified from bovine blood. EC 1.2.1.2.
Entry Term(s): Formate Dehydrogenase; Formate Hydrogenlyases; NAD-Formate Dehydrogenase
Registry Number: EC 1.17.1.9
CAS Type 1 Name: Formate:NAD+ oxidoreductase
Previous Indexing: Aldehyde Oxidoreductases (1973-1979); Formates (1966-1967); Formic Acids (1968-1979); Oxidoreductases (1966-1972)
Public MeSH Note: 91; was see under ALDEHYDE OXIDOREDUCTASES 1980-90
History Note: 91(80); was see under ALDEHYDE OXIDOREDUCTASES 1980-90
Date Established: 1991/01/01
Date of Entry: 1979/05/23
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0008757
Registry Number: EC 1.17.1.9
Scope Note: Flavoproteins that catalyze reversibly the reduction of carbon dioxide to formate. Many compounds can act as acceptors, but the only physiologically active acceptor is NAD. The enzymes are active in the fermentation of sugars and other compounds to carbon dioxide and are the key enzymes in obtaining energy when bacteria are grown on formate as the main carbon source. They have been purified from bovine blood. EC 1.2.1.2.
Terms: Formate Dehydrogenases Preferred Term
Term UI T016877
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1980); NAD-Formate Dehydrogenase
Term UI T016879
Date08/30/1982
LexicalTag NON
ThesaurusID UNK (19XX); Formate Hydrogenlyases
Term UI T016878
Date05/23/1979
LexicalTag NON
ThesaurusID UNK (19XX); Formate Dehydrogenase
Term UI T001004691
Date01/06/2020
LexicalTag NON
ThesaurusID NLM (2021)

Formate Dehydrogenases MeSH Descriptor Data 2024