An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.
Entry Version
HBS
Entry Term(s)
Deoxygenated Sickle Hemoglobin
Deoxyhemoglobin S
Hemoglobin S
Hemoglobin SS
Previous Indexing
Hemoglobins, Abnormal (1966-1972)
Public MeSH Note
77
Online Note
use HEMOGLOBIN, SICKLE to search HEMOGLOBIN S 1973-74 (as Prov)
An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.
