MeSH Browser

MeSH Heading: 5-Hydroxytryptophan
Tree Number(s): D12.125.072.050.850.479
Unique ID: D006916
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D006916
Scope Note: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
Entry Term(s): 5-HTP; Hydroxytryptophan; Oxitriptan; Oxytryptophan; Tryptophan, 5-Hydroxy-
Pharm Action: Antidepressive Agents, Second-Generation
Registry Numbers: C1LJO185Q9
Related Numbers: 56-69-9
CAS Type 1 Name: 2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
Public MeSH Note: 90; was HYDROXYTRYPTOPHAN 1965-89
Online Note: use 5-HYDROXYTRYPTOPHAN to search HYDROXYTRYPTOPHAN 1966-89
History Note: 90; was HYDROXYTRYPTOPHAN 1963-89 (Prov 1963-65)
Date Established: 1965/01/01
Date of Entry: 1999/01/01
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0010787
Registry Numbers: C1LJO185Q9
Related Numbers: 56-69-9
Scope Note: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
Terms: 5-Hydroxytryptophan Preferred Term
Term UI T020806
Date01/01/1999
LexicalTag NON
ThesaurusID; 5-HTP
Term UI T020805
Date03/17/1976
LexicalTag ABB
ThesaurusID UNK (19XX); Oxitriptan
Term UI T020807
Date01/04/1989
LexicalTag NON
ThesaurusID; Oxytryptophan
Term UI T020808
Date02/03/1982
LexicalTag NON
ThesaurusID UNK (19XX); Tryptophan, 5-Hydroxy-
Term UI T668719
Date03/16/2006
LexicalTag NON
ThesaurusID NLM (2007); Hydroxytryptophan
Term UI T020809
Date02/03/1982
LexicalTag NON
ThesaurusID

5-Hydroxytryptophan MeSH Descriptor Data 2025