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Immunoglobulin Switch Region MeSH Descriptor Data 2023


MeSH Heading
Immunoglobulin Switch Region
Tree Number(s)
G05.360.340.024.340.137.430
G05.360.340.024.340.335.300.500
Unique ID
D007134
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D007134
Scope Note
A site located in the INTRONS at the 5' end of each constant region segment of a immunoglobulin heavy-chain gene where recombination (or rearrangement) occur during IMMUNOGLOBULIN CLASS SWITCHING. Ig switch regions are found on genes encoding all five classes (IMMUNOGLOBULIN ISOTYPES) of IMMUNOGLOBULIN HEAVY CHAINS.
Entry Version
IG SWITCH REGION
Entry Term(s)
Heavy-Chain Mu Switch Region
Ig Switch Region
Ig Switch Sequences
Switch Region, Immunoglobulin
Previous Indexing
Genes, Structural (1977-1987)
Immunoglobulin Constant Region (1979-1987)
Immunoglobulin Variable Region (1977-1987)
See Also
Immunoglobulin Class Switching
Public MeSH Note
88
History Note
88
Date Established
1988/01/01
Date of Entry
1987/05/11
Revision Date
2019/07/05
Immunoglobulin Switch Region Preferred
Heavy-Chain Mu Switch Region Narrower
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