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A species of POLYOMAVIRUS, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy. The patient's initials J.C. gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus.
Entry Term(s)
Human Polyomavirus JC
JC polyomavirus
John Cunningham Virus
Polyomavirus hominis 2
Polyomavirus, JC
Registry Numbers
txid10632
Previous Indexing
Papovaviridae (1971-1982)
Polyomaviruses (1971-1982)
Public MeSH Note
2002; see POLYOMAVIRUS HOMINIS 2 1994-2001, see JC VIRUS 1983-93
A species of POLYOMAVIRUS, originally isolated from the brain of a patient with progressive multifocal leukoencephalopathy. The patient's initials J.C. gave the virus its name. Infection is not accompanied by any apparent illness but serious demyelinating disease can appear later, probably following reactivation of latent virus.