MeSH Browser

MeSH Heading: Nogalamycin
Tree Number(s): D02.455.426.559.847.562.050.200.650; D04.615.562.050.200.650; D09.408.051.059.200.650
Unique ID: D009621
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009621
Scope Note: An anthrocycline from a Streptomyces nogalater variant. It is a cytolytic antineoplastic that inhibits DNA-dependent RNA synthesis by binding to DNA.
Entry Term(s): U-15167
Pharm Action: Antibiotics, Antineoplastic
Intercalating Agents
Nucleic Acid Synthesis Inhibitors
Registry Number: L059DCD6IP
Related Numbers: 1404-15-5
CAS Type 1 Name: 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-14-carboxylic acid, 11-((6-deoxy-3-C-methyl-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy)-4-(dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3,5,8,10,13-pentahydroxy-6,13-dimethyl-9,16-dioxo-, methyl ester, (2R-(2alpha,3beta,4alpha,5beta,6alpha,11beta,13alpha,14alpha))-
Previous Indexing: Antibiotics (1966); Antibiotics, Antineoplastic (1967-1975); Glycosides (1966-1975); Naphthacenes (1966-1975)
Public MeSH Note: 91; was see under DAUNORUBICIN 1981-90; was see under NAPHTHACENES 1976-80
History Note: 91(76); was see under DAUNORUBICIN 1981-90; was see under NAPHTHACENES 1976-80
Date Established: 1991/01/01
Date of Entry: 1975/07/23
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Nogalamycin MeSH Descriptor Data 2024