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Oncogenes MeSH Descriptor Data 2023


MeSH Heading
Oncogenes
Tree Number(s)
G05.360.340.024.340.375.500
Unique ID
D009857
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D009857
Annotation
"oncogene" used by author may refer to ONCOGENES or PROTO-ONCOGENES; do not confuse with ONCOGENS see CARCINOGENS; Manual 24.4.4.3; do not confuse with GENES, NEOPLASM
Scope Note
Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of "v-" before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix "c-" before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Entry Term(s)
Oncogene
Transforming Gene
Transforming Genes
NLM Classification #
QZ 210
Previous Indexing
Genes (1966-1977)
Genes, Viral (1978-1982)
Public MeSH Note
83
History Note
83
Date Established
1983/01/01
Date of Entry
1982/04/22
Revision Date
2008/07/08
Oncogenes Preferred
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