MeSH Browser

MeSH Heading: Oncogenes
Tree Number(s): G05.360.340.024.340.375.500
Unique ID: D009857
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D009857
Annotation: "oncogene" used by author may refer to ONCOGENES or PROTO-ONCOGENES; do not confuse with ONCOGENS see CARCINOGENS; Manual 24.4.4.3; do not confuse with GENES, NEOPLASM
Scope Note: Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of v- before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix c- before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Entry Term(s): Oncogene; Transforming Gene; Transforming Genes
NLM Classification #: QZ 210
Previous Indexing: Genes (1966-1977); Genes, Viral (1978-1982)
Public MeSH Note: 83
History Note: 83
Date Established: 1983/01/01
Date of Entry: 1982/04/22
Revision Date: 2008/07/08

Allowable Qualifiers: drug effects (DE)

ethics (ES)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0015298
Scope Note: Genes whose gain-of-function alterations lead to NEOPLASTIC CELL TRANSFORMATION. They include, for example, genes for activators or stimulators of CELL PROLIFERATION such as growth factors, growth factor receptors, protein kinases, signal transducers, nuclear phosphoproteins, and transcription factors. A prefix of v- before oncogene symbols indicates oncogenes captured and transmitted by RETROVIRUSES; the prefix c- before the gene symbol of an oncogene indicates it is the cellular homolog (PROTO-ONCOGENES) of a v-oncogene.
Terms: Oncogenes Preferred Term
Term UI T029232
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1983); Oncogene
Term UI T029231
Date10/10/1989
LexicalTag NON
ThesaurusID NLM (1991); Transforming Gene
Term UI T029233
Date05/09/1987
LexicalTag NON
ThesaurusID NLM (1988); Transforming Genes
Term UI T029234
Date05/09/1987
LexicalTag NON
ThesaurusID UNK (19XX)

Oncogenes MeSH Descriptor Data 2024