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Genes, Tumor Suppressor MeSH Descriptor Data 2022


MeSH Heading
Genes, Tumor Suppressor
Tree Number(s)
G05.360.340.024.340.375.249
G05.360.340.024.340.415.400
Unique ID
D016147
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016147
Annotation
Manual 24.4.4.3
Scope Note
Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.
Entry Term(s)
Anti-Oncogenes
Antioncogenes
Cancer Suppressor Genes
Emerogenes
Genes, Cancer Suppressor
Genes, Growth Suppressor
Genes, Metastasis Suppressor
Genes, Onco-Suppressor
Growth Suppressor Genes
Metastasis Suppressor Genes
Oncogenes, Recessive
Tumor Suppressing Genes
Tumor Suppressor Genes
NLM Classification #
QZ 210
Previous Indexing
Suppression, Genetic (1986-1990)
See Also
Tumor Suppressor Proteins
Public MeSH Note
2002; see GENES, SUPPRESSOR, TUMOR 1991-2001
History Note
2002 (1991)
Date Established
1991/01/01
Date of Entry
1990/05/07
Revision Date
2008/07/08
Genes, Tumor Suppressor Preferred
Metastasis Suppressor Genes Related
Growth Suppressor Genes Broader
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