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Genes, Retinoblastoma MeSH Descriptor Data 2022


MeSH Heading
Genes, Retinoblastoma
Tree Number(s)
G05.360.340.024.340.375.249.400
G05.360.340.024.340.415.400.400
Unique ID
D016161
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016161
Scope Note
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.
Entry Term(s)
Genes, Rb
Rb Genes
Retinoblastoma Genes
NLM Classification #
QZ 210
Previous Indexing
Retinoblastoma/genetics (1972-1990)
See Also
Retinoblastoma
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/05/07
Revision Date
2010/06/25
Genes, Retinoblastoma Preferred
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