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Genes, BRCA2 MeSH Descriptor Data 2022


MeSH Heading
Genes, BRCA2
Tree Number(s)
G05.360.340.024.340.375.249.105
G05.360.340.024.340.415.400.105
Unique ID
D024522
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D024522
Annotation
BRCA stands for "BReast CAncer"
Scope Note
A tumor suppressor gene (GENES, TUMOR SUPPRESSOR) located on human chromosome 13 at locus 13q12.3. Mutations in this gene predispose humans to breast and ovarian cancer. It encodes a large, nuclear protein that is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev 2000;14(11):1400-6)
Entry Term(s)
BRCA2 Gene
Previous Indexing
Genes, Tumor Suppressor (1995-2001)
See Also
BRCA2 Protein
Public MeSH Note
2002
History Note
2002
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2008/07/08
Genes, BRCA2 Preferred
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