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BRCA2 Protein MeSH Descriptor Data 2025


MeSH Heading
BRCA2 Protein
Tree Number(s)
D12.776.313.249
D12.776.624.776.101
D12.776.660.105
Unique ID
D024682
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D024682
Scope Note
A large, nuclear protein, encoded by the BRCA2 gene (GENE, BRCA2). Mutations in this gene predispose humans to breast and ovarian cancer. The BRCA2 protein is an essential component of DNA repair pathways, suppressing the formation of gross chromosomal rearrangements. (from Genes Dev. 2000;14(11):1400-6)
Entry Term(s)
BRCA2 Gene Product
Breast Cancer 2 Gene Product
Breast Cancer 2 Protein
FANCD1 Protein
Fanconi Anemia Complementation Group D1 Protein
Fanconi Anemia Group D1 Complementing Protein
Fanconi Anemia Group D1 Protein
Registry Numbers
0
Previous Indexing
Neoplasm Proteins (1995-2001)
Transcription Factors (1995-2001)
See Also
Hereditary Breast and Ovarian Cancer Syndrome
Public MeSH Note
2002; BCRA2 PROTEIN was indexed under NEOPLASM PROTEINS & TRANSCRIPTION FACTORS 1995-2001
History Note
2002; use BRCA2 PROTEIN (NM) 1995-2001
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2011/06/24
BRCA2 Protein Preferred
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