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Promyelocytic Leukemia Protein MeSH Descriptor Data 2025


MeSH Heading
Promyelocytic Leukemia Protein
Tree Number(s)
D12.776.624.776.654
D12.776.660.745
D12.776.930.713
D12.776.934.500
Unique ID
D000071156
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071156
Scope Note
A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.
Entry Term(s)
RNF71 Protein
TRIM19 Protein
Registry Numbers
0
Previous Indexing
Nuclear Proteins (2008-2016)
Transcription Factors (2008-2016)
Tumor Suppressor Proteins (2008-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/02/26
Promyelocytic Leukemia Protein Preferred
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