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Zinc Fingers MeSH Descriptor Data 2022


MeSH Heading
Zinc Fingers
Tree Number(s)
G02.111.570.820.709.275.500.985
Unique ID
D016335
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016335
Scope Note
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger, one zinc atom is bound to two cysteines and two histidines. In between the cysteines and histidines are 12 residues which form a DNA binding fingertip. By variations in the composition of the sequences in the fingertip and the number and spacing of tandem repeats of the motif, zinc fingers can form a large number of different sequence specific binding sites.
Entry Term(s)
Zinc Finger DNA-Binding Domains
Zinc Finger Motifs
Previous Indexing
Amino Acid Sequence (1987-1990)
DNA-Binding Proteins (1987-1990)
Molecular Sequence Data (1988-1990)
Public MeSH Note
91
History Note
91
Date Established
1991/01/01
Date of Entry
1990/05/29
Revision Date
2017/06/30
Zinc Fingers Preferred
Zinc Finger DNA-Binding Domains Narrower
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