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Immunoreceptor Tyrosine-Based Inhibition Motif MeSH Descriptor Data 2024


MeSH Heading
Immunoreceptor Tyrosine-Based Inhibition Motif
Tree Number(s)
G02.111.570.820.709.275.500.480
Unique ID
D061626
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D061626
Scope Note
A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transduction processes emanating from transmembrane proteins containing IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIFS. The CONSENSUS SEQUENCE of this motif is I(or V)LXYXXL(or V) (where X denotes any amino acid). Also known as ITIM motifs.
Entry Term(s)
Immune Receptor Tyrosine-Based Inhibition Motif
Immuno-Receptor Tyrosine-Based Inhibition Motif
Public MeSH Note
2013
History Note
2013
Date Established
2013/01/01
Date of Entry
2012/07/03
Revision Date
2016/07/05
Immunoreceptor Tyrosine-Based Inhibition Motif Preferred
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