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AAA Domain MeSH Descriptor Data 2022


MeSH Heading
AAA Domain
Tree Number(s)
G02.111.570.820.709.275.500.913
Unique ID
D000074182
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074182
Scope Note
An approximately 250 amino acid domain common to AAA ATPases and AAA Proteins. It consists of a highly conserved N-terminal P-Loop ATPase subdomain with an alpha-beta-alpha conformation, and a less-conserved C-terminal subdomain with an all alpha conformation. The N-terminal subdomain includes Walker A and Walker B motifs which function in ATP binding and hydrolysis.
Entry Term(s)
A-Loop
AAA Domains
AAA Modules
AAA+ Domain
AAA+ Modules
P-Loop
Walker A Motif
Walker B Motif
Walker Motif
Walker Motifs
Previous Indexing
Amino Acid Sequence (1990-2017)
See Also
ATPases Associated with Diverse Cellular Activities
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/02/24
AAA Domain Preferred
Walker Motifs Narrower
A-Loop Related
Walker B Motif Narrower
Walker A Motif Narrower
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