MeSH Browser

MeSH Heading: MYND Domains
Tree Number(s): G02.111.570.820.709.275.500.985.375; G02.111.570.820.709.275.750.500.474
Unique ID: D000074608
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000074608
Scope Note: Zinc finger domains (named for myeloid, Nervy and DEAF-1) that occur in a variety of eukaryotic proteins, including RUNT-RELATED TRANSCRIPTION FACTOR 1 . They are characterized by a cluster of cysteine and histidine residues with conserved spacing that forms the zinc-binding motif and have beta-beta-alpha (see BETA-SHEET and ALPHA-HELIX) topology, similar to LIM domains (see LIM DOMAIN PROTEINS) and RING FINGER DOMAINS. MYND domains function as protein interaction motifs and have affinity for PROLINE-RICH PROTEIN DOMAINS.
Entry Term(s): MYND Domain; MYND Motif; Zinc Finger MYND-Type
Previous Indexing: Protein Structure, Tertiary (1998-2017)
Public MeSH Note: 2018
History Note: 2018
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M000627133
Scope Note: Zinc finger domains (named for myeloid, Nervy and DEAF-1) that occur in a variety of eukaryotic proteins, including RUNT-RELATED TRANSCRIPTION FACTOR 1 . They are characterized by a cluster of cysteine and histidine residues with conserved spacing that forms the zinc-binding motif and have beta-beta-alpha (see BETA-SHEET and ALPHA-HELIX) topology, similar to LIM domains (see LIM DOMAIN PROTEINS) and RING FINGER DOMAINS. MYND domains function as protein interaction motifs and have affinity for PROLINE-RICH PROTEIN DOMAINS.
Terms: MYND Domains Preferred Term
Term UI T000916619
Date03/02/2017
LexicalTag ACX
ThesaurusID NLM (2018); Zinc Finger MYND-Type
Term UI T000916621
Date03/02/2017
LexicalTag ACX
ThesaurusID NLM (2018); MYND Motif
Term UI T000916627
Date03/02/2017
LexicalTag ACX
ThesaurusID NLM (2018); MYND Domain
Term UI T000916620
Date03/02/2017
LexicalTag ACX
ThesaurusID NLM (2018)

MYND Domains MeSH Descriptor Data 2024