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WW Domains MeSH Descriptor Data 2022


MeSH Heading
WW Domains
Tree Number(s)
G02.111.570.820.709.275.750.500.937
Unique ID
D000074585
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074585
Scope Note
An approximately 40 amino acid protein domain that occurs in a variety of unrelated proteins and may be repeated up to four times in some proteins. It is characterized by two TRYPTOPHAN residues (WW) about 20 amino acids apart and folds into a stable triple-stranded BETA-SHEET. It binds PROLINE-RICH PROTEIN DOMAINS and PHOSPHOSERINE or PHOSPHOTHREONINE-containing protein domains that occur in many signal-transducing and cytoskeletal proteins such as DYSTROPHIN.
Entry Term(s)
WW Domain
Previous Indexing
Amino Acid Sequence (1996-2017)
Protein Structure, Tertiary (1999-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2019/07/05
WW Domains Preferred
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