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Death Domain Superfamily MeSH Descriptor Data 2025


MeSH Heading
Death Domain Superfamily
Tree Number(s)
G02.111.570.820.709.275.750.500.395
Unique ID
D000071458
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071458
Scope Note
A family of structurally-related protein interaction domains characterized by 6-helical closed bundle fold, with Greek key topology and an internal pseudo two-fold symmetry. Death-like domains occur in many proteins that are essential for APOPTOSIS, including CASPASE RECRUITMENT DOMAIN CONTAINING PROTEINS and DEATH DOMAIN RECEPTORS.
Entry Term(s)
Death-Like Domain
Death-Like Domains
Previous Indexing
Amino Acid Sequence (2001-2016)
Apoptosis (2001-2016)
Molecular Sequence Data (2001-2016)
Protein Structure, Tertiary (2007-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/05/09
Death Domain Superfamily Preferred
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