MeSH Browser

MeSH Heading: Death Domain Superfamily
Tree Number(s): G02.111.570.820.709.275.750.500.395
Unique ID: D000071458
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000071458
Scope Note: A family of structurally-related protein interaction domains characterized by 6-helical closed bundle fold, with Greek key topology and an internal pseudo two-fold symmetry. Death-like domains occur in many proteins that are essential for APOPTOSIS, including CASPASE RECRUITMENT DOMAIN CONTAINING PROTEINS and DEATH DOMAIN RECEPTORS.
Entry Term(s): Death-Like Domain; Death-Like Domains
Previous Indexing: Amino Acid Sequence (2001-2016); Apoptosis (2001-2016); Molecular Sequence Data (2001-2016); Protein Structure, Tertiary (2007-2016)
Public MeSH Note: 2017
History Note: 2017
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/09

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Chemical Phenomena [G02]
- Biochemical Phenomena [G02.111]
  - Molecular Structure [G02.111.570]
    - Molecular Conformation [G02.111.570.820]
      - Protein Conformation [G02.111.570.820.709]
        
        Protein Structural Elements [G02.111.570.820.709.275]
        
        Protein Domains [G02.111.570.820.709.275.750]
        
        Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]
        
        Ankyrin Repeat [G02.111.570.820.709.275.750.500.080]
        
        B30.2-SPRY Domain [G02.111.570.820.709.275.750.500.290]
        
        BTB-POZ Domain [G02.111.570.820.709.275.750.500.343]
        
        Death Domain Superfamily [G02.111.570.820.709.275.750.500.395]
        
        Caspase Activation and Recruitment Domain [G02.111.570.820.709.275.750.500.395.250]
        
        Death Domain [G02.111.570.820.709.275.750.500.395.500]
        
        Death Effector Domain [G02.111.570.820.709.275.750.500.395.750]
        
        Pyrin Domain [G02.111.570.820.709.275.750.500.395.875]
        
        FERM Domains [G02.111.570.820.709.275.750.500.422]
        
        Kelch Repeat [G02.111.570.820.709.275.750.500.448]
        
        MYND Domains [G02.111.570.820.709.275.750.500.474]
        
        PDZ Domains [G02.111.570.820.709.275.750.500.500]
        
        RING Finger Domains [G02.111.570.820.709.275.750.500.625]
        
        src Homology Domains [G02.111.570.820.709.275.750.500.750]
        
        Sterile Alpha Motif [G02.111.570.820.709.275.750.500.813]
        
        Tetratricopeptide Repeat [G02.111.570.820.709.275.750.500.829]
        
        Tudor Domain [G02.111.570.820.709.275.750.500.844]
        
        WD40 Repeats [G02.111.570.820.709.275.750.500.875]
        
        WW Domains [G02.111.570.820.709.275.750.500.937]

Death Domain Superfamily Preferred

Death Domain Superfamily MeSH Descriptor Data 2024