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Caspase Activation and Recruitment Domain MeSH Descriptor Data 2022


MeSH Heading
Caspase Activation and Recruitment Domain
Tree Number(s)
G02.111.570.820.709.275.750.500.395.250
Unique ID
D000071476
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071476
Scope Note
A homotypic protein interaction module of the death domain superfamily. It is composed of a bundle of six alpha-helices that is related in sequence and structure to the DEATH DOMAIN and DEATH EFFECTOR DOMAIN. The Caspase Activation and Recruitment Domain (CARD domain) typically associates with other CARD-containing proteins, forming either dimers or trimers. CARD domains may occur in isolation, or in combination with other domains in CARD signaling adaptor proteins and initiator CASPASES that function in APOPTOSIS.
Entry Term(s)
CARD Domain
CARD Domains
Caspase Activation and Recruitment Domains
Caspase Recruitment Domain
Caspase Recruitment Domains
Previous Indexing
Amino Acid Sequence (1997-2016)
Apoptosis Regulatory Proteins (2006-2016)
CARD Signaling Adaptor Proteins (2006-2016)
See Also
CARD Signaling Adaptor Proteins
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/05/09
Caspase Activation and Recruitment Domain Preferred
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