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Pyrin Domain MeSH Descriptor Data 2023


MeSH Heading
Pyrin Domain
Tree Number(s)
G02.111.570.820.709.275.750.500.395.875
Unique ID
D000071196
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071196
Scope Note
A protein interaction domain of the death domain superfamily. It is characterized by a 6-helix bundle similar to those that occur in DEATH DOMAIN RECEPTORS. Pyrin domains are present in a variety of proteins, especially those that function in INFLAMMASOMES; AUTOPHAGY; and APOPTOSIS. They form homodimers or heterodimers with death domain proteins to facilitate the assembly of signaling complexes.
Entry Term(s)
DAPIN Domain
PAAD-DAPIN-PYRIN Domain
PADD Domain
PYD Domain
Previous Indexing
Cytoskeletal Proteins (2001-2016)
Protein Structure, Tertiary (2001-2016)
See Also
Pyrin
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/05/09
Pyrin Domain Preferred
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